Melpomeni Platani

CysNet infers cysteine redox proteoforms from mass spectrometry data, resolving oxiform states and quantifying their abundance in human stem cells.

ReCap enables redox proteomics by preserving redox states and scaling oxidation to protein copy numbers, revealing sparse and quantitatively concentrated cysteine oxidation signals.

This study identifies PHD1-dependent hydroxylation of RepoMan at P604, showing it regulates mitotic progression by modulating PP2A interaction and H3T3 phosphorylation.

This study compares the proteomes of human induced pluripotent stem cells (hiPSCs) and embryonic stem cells (hESCs), finding quantitative differences in protein expression affecting growth, metabolism, and secreted factors.