Author

Xiaoxuan Su

Scripps Research InstituteORCID 0000-0003-3902-2357Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

Matthew David DisneyiD· 2 shared Ryuichi Sekioka· 2 shared Xueyi YangiD· 2 shared Amirhossein TaghaviiD· 1 shared Jessica L. Childs‐DisneyiD· 1 shared Jielei WangiD· 1 shared Kisu SungiD· 1 shared Patrick R. A. ZanoniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

Matthew David DisneyORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintAug 26, 2026

Programmable Recruitment of RNA-Binding Proteins Enables Small Molecule-Directed Destabilization of Nuclear Pre-mRNA

Xiaoxuan Su, Jielei Wang, Takahiro M. Ishii…·Matthew David Disney

This paper develops a programmable platform to recruit RNA-binding proteins using small molecules, enabling RNA destabilization, and demonstrates its application to MAPT pre-mRNA.

DOI 10.64898/2026.08.25.746729

humanexperimental assay

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BiochemistrybioRxivPreprintNov 5, 2025

Live-Cell Covalent Profiling Reveals Principles of RNA-Small Molecule Recognition across the Human Transcriptome

Yuquan Tong, Amirhossein Taghavi, Xiaoxuan Su…·Matthew David Disney

The paper develops a live-cell method to identify RNA-small molecule interactions and uses it to design selective RNA degraders.

1 citation

humanproteomics

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