Natalie Prystajecky

The paper detects a reassortant H3N2 influenza A virus in farmed mink in British Columbia, linked to swine and human origins, highlighting zoonotic risks and the need for surveillance.

The paper develops a targeted genomic sequencing method to detect influenza A viruses in wetland sediments, identifying diverse HA and NA subtypes including H5 from environmental samples.

ProbeTools designs hybridization probes for viral sequencing, validated with a panel targeting influenza A virus HA and NA segments, showing high coverage and enrichment in silico and in vitro.

The paper optimizes a magnetic bead-based nucleic acid extraction protocol for SARS-CoV-2 testing to reduce cross-well contamination while maintaining sensitivity.

V3 primer pools with 22 extra alternates improve coverage; revised library preps raise double-barcode demultiplexing from 42.15% to 74.5%, cut misassignment 35x and bring reagent cost near £10 per sample.

This study examines the spatiotemporal dynamics of riverine microbial communities, including viruses, bacteria, and microeukaryotes, revealing distinct patterns and highlighting the need for holistic analysis.

Neptune identifies differentially abundant genomic loci in bacterial populations using k-mer matching and probabilistic models, showing sensitivity and specificity on simulated and real data.

This study identifies antibiotic resistance genes in agricultural and urban watersheds using metagenomics and qPCR, finding higher ARG abundance in impacted sites.