Author

James Millard

University of LiverpoolORCID 0000-0001-6427-552XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Research Focus:phylogenetics / evolution· 1

Frequent Co-Authors

Alexander S. PymiD· 2 shared Camus NimmoiD· 2 shared Louis GrandjeaniD· 2 shared Max R. O’DonnelliD· 2 shared Adrie J. C. SteyniD· 1 shared Ajit LalvaniiD· 1 shared Alexander S. LachapelleiD· 1 shared Alice E. BrankiniD· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersGenomics

Alexander S. PymORCID

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3 papers

Recent·Most cited

GenomicsNature CommunicationsPeer-reviewedJan 12, 2024

Quantitative measurement of antibiotic resistance in Mycobacterium tuberculosis reveals genetic determinants of resistance and susceptibility in a target gene approach

Ivan Barilar, Simone Battaglia, Emanuele Borroni…·Guy Edward Thwaites

This study quantifies antibiotic resistance in tuberculosis using genomic data and MIC measurements to identify genetic determinants of resistance and hypersensitivity across multiple drugs.

56 citationstop 1%

humanwhole-genome sequencing

𝕏 PostBluesky

GenomicsbioRxivPreprintOct 6, 2020

Detection of a historic reservoir of bedaquiline / clofazimine resistance associated variants in Mycobacterium tuberculosis

Camus Nimmo, Arturo Torres Ortiz, Juanita Pang…·Lucy van Dorp

The paper identifies pre-existing bedaquiline resistance variants in Mycobacterium tuberculosis genomes before clinical use of the drug, highlighting the need for rapid susceptibility testing.

4 citations

humanwhole-genome sequencing

𝕏 PostBluesky

GeneticsAntimicrobial Agents and ChemotherapyPeer-reviewedJan 16, 2020

N-acetyltransferase 2 genotypes amongst ulu Speaking South Africans and isoniazid / N-acetyl-isoniazid pharmacokinetics during ant-tuberculosis treatment

Thuli Mthiyane, James Millard, John Adamson…·Alexander S. Pym

The paper investigates NAT2 polymorphisms and their effect on isoniazid pharmacokinetics in HIV-infected South Africans with tuberculosis, finding no significant genotype-phenotype correlation.

31 citations

humanstatistical model

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