A highly conserved neuronal microexon in DAAM1 controls actin dynamics, RHOA/ROCK signaling, and memory formation
Patryk Poliński, Marta Miret-Cuesta, Alfonsa Zamora‐Moratalla…·Manuel Irimia
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Barcelona Institute of Science and TechnologyORCID 0000-0001-6451-1094Unclaimed ORCID profile · follow to get notified of new preprints
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3 papers
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Patryk Poliński, Marta Miret-Cuesta, Alfonsa Zamora‐Moratalla…·Manuel Irimia
Cèsar Sierra, Miguel Sabariego-Navarro, Álvaro Fernández‐Blanco…·Mara Dierssen
The paper uses single nucleus RNA-seq to analyze the hippocampus of a Down syndrome mouse model, identifying transcriptomic changes and a novel long-non-coding gene involved in cognitive phenotypes.
Álvaro Fernández‐Blanco, Alfonsa Zamora‐Moratalla, Miguel Sabariego-Navarro, Mara Dierssen
This study investigates engram formation in a Down syndrome mouse model and finds reduced engram cell numbers and impaired neuronal function in the dentate gyrus.