Author

Francisco Monroy

Universidad Complutense de MadridORCID 0000-0001-6455-3083Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Diego Herráez‐AguilariD· 2 shared Agustín LahoziD· 1 shared Alberto Mora PerdigueroiD· 1 shared Ana García GarcíaiD· 1 shared Antonio Giráldez Trujillo· 1 shared Carlos del Pozo-RojasiD· 1 shared Clara Luque‐RiojaiD· 1 shared David Calzón LozanoiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiophysics

Diego Herráez‐AguilarORCID

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2 papers

Recent·Most cited

BiophysicsThe FASEB JournalPeer-reviewedNov 19, 2025

Metabolic Rigidity as a Mechanical Barrier to Malaria: Flickering Loss in PKLR-Deficient Erythrocytes

Natalia Hernando‐Ospina, Macarena Calero, Guillermo Solís‐Fernández…·Francisco Monroy

This study shows that PKLR-deficient erythrocytes, due to metabolic rigidity, resist Plasmodium yoelii infection by maintaining mechanical properties that hinder parasite-induced membrane changes.

1 citation

mouseimaging

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Cancer BiologyNature CommunicationsPeer-reviewedFeb 16, 2025

ELOVL6 as a Therapeutic Target: Disrupting c-MYC-Driven Lipid Metabolism to Enhance Chemotherapy in Pancreatic Cancer

Ana García García, María Ferrer Aporta, Germán Vallejo-Palma…·Victor Javier Sanchez-Arevalo Lobo

This study identifies ELOVL6 as a therapeutic target in pancreatic cancer by showing its role in c-MYC-driven lipid metabolism and its impact on chemotherapy efficacy.

21 citationstop 1%

mousehuman

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