Julie L. Lefebvre

TRACR is a transneuronal tracing system that uses synthetic Notch technology to label postsynaptic neurons and analyze circuit connectivity in the mouse visual system.

The paper identifies molecular pathways associated with neurodevelopmental disorder subgroups using neuroimaging data from mice and humans.

This study shows that gamma-Protocadherins mediate filopodia self-recognition and contact-induced retractions, which are essential for dendrite self-avoidance in mammalian neurons.

This study shows Pten and Dscam regulate amacrine cell spacing through endocytic trafficking of cell adhesion and signaling molecules, with altered extracellular vesicles and Wnt signaling in Pten mutants.

This study shows that γ-protocadherin isoforms are critical for synapse formation and peripheral branching in touch sensory neurons, and their loss disrupts corticospinal synapses.

The paper uses morphology-based pseudotime and fate mapping to show cerebellar inhibitory interneurons diversify into two classes with within-class heterogeneity.

This study shows that gamma-Protocadherins are essential for the survival of GABAergic interneurons during development, preventing excessive apoptosis and ensuring proper inhibitory network formation.