Dylan C. Lam

The paper introduces PerturbPair, a platform integrating transcriptomic and optical screens to map macrophage regulatory networks, revealing cross-modal relationships and disease-relevant gene programs.

The paper investigates how RNA folding influences host mRNA partitioning into Ebola virus condensates under different conditions and identifies implications for viral-host co-evolution.

Bento enables subcellular analysis of spatial transcriptomics data by defining domains, annotating localization patterns, and quantifying gene colocalization, demonstrating its use on multiple datasets.