Brendon M. Lee

This study shows desiccation-induced DNA damage in Mtb leads to mutations and drug resistance by affecting DNA repair and gene expression.

This study uses ancestral sequence reconstruction to explore PET-degrading cutinase sequence space, revealing diverse evolutionary pathways and the effectiveness of LASE in mapping fitness landscapes.

This study identifies mutations in Mycobacterium tuberculosis that confer resistance to nitroimidazole antibiotics, highlighting the need for monitoring these mutations to manage antibiotic use.