A. M. Saleh

The paper shows BRCA2 loss leads to a PKM1-dominant glycolytic state that can be targeted with PKM activators to kill HRD tumors.

This study identifies PspA's role in maintaining membrane potential and supporting NADH dehydrogenase function in mycobacteria through interactions with PspM and menaquinone.

This study investigates the roles of CydAB and Nox in E. faecalis metabolism under aerobic and hypoxic conditions, revealing Nox as the primary oxygen consumer and highlighting the complementary roles of respiratory and oxidative pathways.

This study shows desiccation-induced DNA damage in Mtb leads to mutations and drug resistance by affecting DNA repair and gene expression.

The paper visualizes zinc-starved, slow-replicating Mycobacterium tuberculosis using a fluorescent reporter and shows increased expression in neutrophil-rich lung lesions during infection.

The paper profiles gut bacterial extracellular vesicles (bEVs) and links their cargo composition to host transcriptional responses across different cell types.

The paper identifies Rv2571c as a mycobacterial ion channel that mediates pyrazinamide resistance by regulating cytoplasmic acidification.

This paper identifies GlmU as a critical enzyme inhibited by sugar phosphates in Vibrio cholerae, linking glucose metabolism to cell envelope integrity and antibiotic susceptibility.