Elizabeth M. Sefton

This study uses single-cell RNA sequencing to identify brown fat precursors and demonstrates their in vitro differentiation into functional brown adipocytes.

This study identifies fibroblast-derived HGF as critical for diaphragm muscularization and phrenic nerve development, showing its role in muscle progenitor recruitment and maintenance.

The paper describes a cell culture system using mouse pleuroperitoneal fold fibroblasts to functionally test candidate genes and pathways for congenital diaphragmatic hernias.

This study identifies unique genetic programs for neck muscles and connective tissues in mammals using a 3D model and lineage analysis in mice.

This paper describes the developmental origin and morphogenesis of the diaphragm in mice, identifying key events and their role in congenital diaphragmatic hernia.