BiophysicsProtein SciencePeer-reviewed
Quantitative analysis of inhibitor-induced assembly disruption in human UDP-GlcNAc 2-epimerase using mass photometry
Nico Boback, Jacob Lucián Gorenflos López, Christian P. R. Hackenberger…·Daniel Christian Lauster
The paper uses mass photometry to analyze how small-molecule inhibitors disrupt GNE oligomerization, finding concentration-dependent destabilization and competitive binding.
DOI 10.1002/pro.70335