A. Nicole Fox

The paper shows mitotic chromosomes are self-entangled and disentangle through a Topoisomerase II-dependent two-stage process during mitotic exit.

The paper investigates mitotic chromosome architecture across species and cell types, finding species-specific loop sizes but no cell type differences, and links loop size to chromosome arm compaction.

The paper identifies glial TGFβ signaling as essential for axon survival and shows its loss leads to age-dependent neurodegeneration.

The paper shows that during telophase, condensin-mediated loops are replaced by cohesin-mediated loops and TADs, revealing telophase as a critical transition in chromosome folding.