Hugo B. Brandão

This study shows that replisomes block SMC-mediated DNA-loop extrusion in Bacillus subtilis by restricting SMC translocation, with occasional bypass events observed.

This study characterizes the organization of Borrelia burgdorferi's segmented genome and interactions between replicons using Hi-C, revealing chromosome structure and plasmid interactions.

The paper shows that transcribing RNA polymerases act as moving barriers to cohesin, altering chromatin organization near active genes.

The paper shows cohesin-dependent loop extrusion organizes zygotic chromatin into loops and domains, with distinct effects on maternal and paternal genomes.

This study investigates cell-to-cell and cell-intrinsic variability in genome organization using Hi-C and genome imaging in human fibroblasts, revealing extensive heterogeneity in chromatin conformations.