Sebastian Schürmann

Coordinated IFN-γ/TNF Axis Drives Selective Loss of Activated Enteric Glia in Inflammatory Bowel Diseases

This study identifies IBD type-associated EGC activation signatures and reveals TNF/IFN-γ-driven necroptosis of activated enteric glia in inflammatory bowel diseases.

IBDome: An integrated molecular, histopathological, and clinical atlas of inflammatory bowel diseases

This study integrates multi-omic and multimodal data from IBD patients to identify molecular, histopathological, and clinical features associated with inflammatory bowel diseases.

SEMPAI: a Self-Enhancing Multi-Photon Artificial Intelligence for prior-informed assessment of muscle function and pathology

SEMPAI integrates hypothesis-driven priors into a deep learning framework to analyze multiphoton microscopy data of muscle fibers, outperforming existing methods in predictive tasks.

Targeting xCT-Mediated Glutamate Release Normalizes Tumor Angiogenesis In The Brain

This study shows that targeting xCT reduces tumor angiogenesis in brain tumors by affecting endothelial cells via glutamate and NMDAR.