Alpana Singh

The paper detects mitotic neuroblasts in adult murine and human small intestinal myenteric plexus, providing evidence of steady-state neurogenesis.

This study shows stress-induced glucocorticoid signaling reduces BDNF-TrkB signaling in the enteric nervous system, leading to GI dysmotility, and identifies TrkB as a potential therapeutic target.

This study shows that age-related changes in the lineage composition of the enteric nervous system affect gut health, with mesoderm-derived neurons becoming dominant and functional effects on intestinal motility that can be reversed by GDNF.