Author

Ainsleigh Scott

Beth Israel Deaconess Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

Jared SlosbergiD· 3 shared Philippa SeikaiD· 3 shared Srinivas N. Puttapaka· 3 shared Su Min HongiD· 3 shared Subhash KulkarniiD· 3 shared Alan ConsortiiD· 1 shared Alpana SinghiD· 1 shared Gamze SönmeziD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersNeuroscience

Jared SlosbergORCID

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3 papers

Recent·Most cited

Enteric neurons modulate colorectal cancer cell cycle through a PCSK1 - Methionine-Enkephalin Axis

Philippa Seika, Srinivas N. Puttapaka, Su Min Hong, Ainsleigh Scott, Jared Slosberg, Stefânia Bovo Minto, Kevin M. Haigis, Subhash Kulkarni

This study identifies a neuronal PCSK1-M-ENK pathway in the ENS that suppresses colorectal cancer growth through OGFr activation.

bioRxiv · May 6, 2026 · PreprintCancer Biology

Reduced enteric Bdnf expression and TrkB-dependent regulation of Vip in a Mecp2-null mouse model of Rett syndrome-associated gastrointestinal dysmotility

Srinivas N. Puttapaka, Israel Abebe Admasu, Ainsleigh Scott, Gamze Sönmez, Philippa Seika, Mahalakshmi Rajkumar, Xavier Valencia, Alan Consorti, Su Min Hong, Jared Slosberg, Michela Fagiolini, Subhash Kulkarni

This study identifies reduced enteric Bdnf and altered VIPergic signaling as key mechanisms of GI dysmotility in a Mecp2-null mouse model of Rett syndrome.

bioRxiv · Apr 15, 2026 · PreprintNeuroscience

Reduced enteric BDNF-TrkB signaling drives stress-dependent glucocorticoid-mediated GI dysmotility

Jared Slosberg, Srinivas N. Puttapaka, Philippa Seika, Su Min Hong, Alpana Singh, Ainsleigh Scott, Subhash Kulkarni

This study shows stress-induced glucocorticoid signaling reduces BDNF-TrkB signaling in the enteric nervous system, leading to GI dysmotility, and identifies TrkB as a potential therapeutic target.

bioRxiv · Dec 13, 2024 · PreprintNeuroscience