Author

Silvia Hormeño

Consejo Superior de Investigaciones CientíficasORCID 0000-0001-6549-357XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Clara Aicart-RamosiD· 2 shared Edwin AntonyiD· 2 shared Fernando Moreno‐HerreroiD· 2 shared Mark Simon DillinghamiD· 2 shared Oliver J. WilkinsoniD· 2 shared Ayush MistryiD· 1 shared Sahiti KuppaiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 20 mutual co-author links

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2 shared papersBiochemistry

Clara Aicart-RamosORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintJul 17, 2026

Structural elements required for the efficient loading and activation of HELB on RPA-coated single-stranded DNA

Oliver J. Wilkinson, Silvia Hormeño, Clara Aicart-Ramos…·Mark Simon Dillingham

This paper identifies two structural elements in HELB essential for its interaction with RPA-coated ssDNA, showing how they facilitate RPA displacement and DNA loop formation.

DOI 10.64898/2026.07.16.738708

humanproteomics

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Molecular BiologybioRxivPreprintMay 27, 2021

Human HELB is a processive motor protein which catalyses RPA clearance from single-stranded DNA

Silvia Hormeño, Oliver J. Wilkinson, Clara Aicart-Ramos…·Fernando Moreno‐Herrero

This study characterizes human HELB as a monomeric helicase that binds ssDNA, hydrolyzes ATP, and clears RPA from ssDNA through translocation.

1 citation

humanbulk RNA-seq

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