Avishay Spitzer

The paper identifies transcriptional programs in fibroblastic foci fibroblasts using spatial and single-cell transcriptomics, revealing MMP11 as a prognostic biomarker and potential therapeutic target.

This study uses single-cell RNA sequencing to identify subtypes and proliferation patterns in small intestine neuroendocrine tumors, revealing non-proliferative neuroendocrine cells and proliferative non-malignant cells.

This study shows that BDNF-TrkB signaling promotes malignant synaptic plasticity in gliomas, enhancing tumor progression through mechanisms similar to long-term potentiation in the healthy brain.