Author

Debdatta Halder

Icahn School of Medicine at Mount SinaiORCID 0009-0004-0780-7832Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Alan SotoiD· 1 shared Amit TiroshiD· 1 shared Andrew ElliottiD· 1 shared Ari VanderWaldeiD· 1 shared Avishay SpitzeriD· 1 shared Balazs HalmosiD· 1 shared Chaya Barbolin· 1 shared Dan HassoniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Alan SotoORCID

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2 papers

Recent·Most cited

ATM functions as a rheostat of metabolic stress in small-cell lung cancer

Debdatta Halder, Utsav Sen, Vrinda Jethalia, Subhamoy Chakraborty, Andrew Elliott, Kedwin Ventura, Ari VanderWalde, Balazs Halmos, Hossein Borghaei, Tin Htwe Thin, Alan Soto, Mirela Berisa, Rachel Brody, Deniz Demircioglu, Dan Hasson, Triparna Sen

This study shows ATM regulates metabolic stress in SCLC by affecting ATF4 and MYC, leading to ferroptotic cell death and revealing a new therapeutic target.

bioRxiv · Mar 17, 2026 · PreprintCancer Biology

Subtypes and proliferation patterns of small intestine neuroendocrine tumors revealed by single cell RNA sequencing

Einav Someach, Debdatta Halder, Avishay Spitzer, Chaya Barbolin, Michael Tyler, Reut Halperin, Moshe Biton, Amit Tirosh, Itay Tirosh

This study uses single-cell RNA sequencing to identify subtypes and proliferation patterns in small intestine neuroendocrine tumors, revealing non-proliferative neuroendocrine cells and proliferative non-malignant cells.

eLife · Oct 21, 2024Peer-reviewedCancer Biology