Enterococcal Polysaccharide Antigen (EPA) rhamnan backbone contributes to cell wall architecture and is essential for antimicrobial resistance, innate immune evasion and phage infection
Lea Kupcova, Nishan Nathoo, Bartosz J. Michno…·Stéphane Mesnage
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Jagiellonian UniversityORCID 0000-0001-6562-8630Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Lea Kupcova, Nishan Nathoo, Bartosz J. Michno…·Stéphane Mesnage
Bartosz J. Michno, Niedharsan Pooranachandran, THEOBALD SMITH…·Tomasz K. Prajsnar
This study identifies non-canonical autophagy pathways, including LC3-associated phagocytosis and STIL, that mediate host defense against pneumococcal infection in zebrafish.
Clare F. Muir, Constantino Carlos Reyes‐Aldasoro, Tomasz K. Prajsnar…·Stephen A. Renshaw
The paper identifies pulsatile Class I PI3K activity on neutrophil phagosomes during bacterial infection, suggesting phagosomes reopen and reclose to release or restart digestion.
Robert E Smith, Bartosz J. Michno, Lowrence Rene Christena…·Stéphane Mesnage
This paper identifies AtlE, an N-acetylmuramidase essential for virulence in E. faecalis, showing its role in cell wall remodelling and immune evasion via the release of EPA-containing fragments.