Stephen A. Renshaw

This study shows verapamil reduces inflammation in cystic fibrosis by normalizing epithelial calcium signaling and oxidative stress in zebrafish and human cells.

The paper identifies pulsatile Class I PI3K activity on neutrophil phagosomes during bacterial infection, suggesting phagosomes reopen and reclose to release or restart digestion.

This study shows curcumin improves inflammation and tissue damage in cystic fibrosis by restoring NRF2 activity in zebrafish and patient-derived airway organoids.

This study shows that macrophage transplantation rescues RNASET2-deficient leukodystrophy in zebrafish by replacing dysfunctional microglia, reducing neuroinflammation and restoring motor function.

This study identifies dysfunctional microglia in a zebrafish model of RNASET2-deficient leukoencephalopathy as a key contributor to pathological apoptosis and behavioral defects.