NeurosciencebioRxivPreprint
Pathological tau activates inflammatory nuclear factor-kappa B (NF-κB) and pT181-Qβ vaccine attenuates NF-κB in PS19 tauopathy mice
Karthikeyan Tangavelou, Shanya Jiang, Somayeh Dadras…·Kiran Bhaskar
The paper shows that pathological tau activates NF-κB in microglia and that a pT181-Qβ vaccine reduces NF-κB activity in tauopathy mice.
DOI 10.1101/2025.03.10.642500