Michael A. Mandell

A role for CASM in the repair of damaged Golgi architecture

This study shows that CASM helps repair damaged Golgi structure by coordinating with lysosomal biogenesis in TRIM46-deficient cells.

Pathological tau activates inflammatory nuclear factor-kappa B (NF-κB) and pT181-Qβ vaccine attenuates NF-κB in PS19 tauopathy mice

The paper shows that pathological tau activates NF-κB in microglia and that a pT181-Qβ vaccine reduces NF-κB activity in tauopathy mice.