Julianne Peabody

This paper develops a VLP-based immunogen, MS2.87-97, that elicits anti-Myostatin antibodies, increases muscle mass and strength, and reduces adiposity in mice.

The paper shows that pathological tau activates NF-κB in microglia and that a pT181-Qβ vaccine reduces NF-κB activity in tauopathy mice.

This study compares two VLP-based vaccines targeting different pTau epitopes, finding that the PHF1 vaccine reduces tau pathology and restores cognition better than the AT8 vaccine in a mouse model.