Author

Andreas Köhler

Umeå UniversityORCID 0000-0001-6571-2162Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1 Organism:yeast· 1

Frequent Co-Authors

Alissa BenediktiD· 1 shared Antonio ScialdoneiD· 1 shared Francesco PadovaniiD· 1 shared I. V. KukhtevichiD· 1 shared Jan Marcel SkotheimiD· 1 shared Juha SaarikangasiD· 1 shared Jurgita PaukštytėiD· 1 shared Kim Job· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Alissa BenediktORCID

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1 paper

Recent·Most cited

Retrograde signalling mediates cellular adaptation to mitochondrial DNA copy number alterations

Alissa Benedikt, Kim Job, Xiaoping Li, Soumodeep Sarkar, Luisa Hernández Götz, I. V. Kukhtevich, Francesco Padovani, Yagya Chadha, Jurgita Paukštytė, Juha Saarikangas, Jan Marcel Skotheim, Robert Schneider, Matthew P. Swaffer, Antonio Scialdone, Michael Charles Lanz, , Kurt M. Schmoller

This study shows that yeast cells adapt to changes in mitochondrial DNA copy number through retrograde signaling and protein dosage compensation, allowing robust growth despite mtDNA fluctuations.

bioRxiv · Apr 24, 2026 · PreprintCell Biology