Author

Alissa Benedikt

Helmholtz MunichORCID 0009-0007-3515-878XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1 Organism:yeast· 1

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Andreas KöhleriD· 1 shared Antonio ScialdoneiD· 1 shared Francesco PadovaniiD· 1 shared I. V. KukhtevichiD· 1 shared Jan Marcel SkotheimiD· 1 shared Juha SaarikangasiD· 1 shared Jurgita PaukštytėiD· 1 shared Kim Job· 1 shared

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2026-2026 · peak 1/yr

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Andreas KöhlerORCID

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1 paper

Recent·Most cited

Cell BiologybioRxivPreprintApr 24, 2026

Retrograde signalling mediates cellular adaptation to mitochondrial DNA copy number alterations

Alissa Benedikt, Kim Job, Xiaoping Li…·Kurt M. Schmoller

This study shows that yeast cells adapt to changes in mitochondrial DNA copy number through retrograde signaling and protein dosage compensation, allowing robust growth despite mtDNA fluctuations.

DOI 10.64898/2026.04.22.720057

yeastDNA methylation

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