Yagya Chadha

Single-cell imaging reveals a key role of Bck2 in budding yeast cell size adaptation to nutrient challenges

The paper uses single-cell imaging and machine learning to show Bck2 is critical for yeast cell size adaptation to nutrient changes, unlike in steady-state conditions.

SpotMAX: a generalist framework for multi-dimensional automatic spot detection and quantification

SpotMAX is an AI-driven framework for automated spot detection and quantification in microscopy data, outperforming existing tools and human annotators across diverse biological applications.

Retrograde signalling mediates cellular adaptation to mitochondrial DNA copy number alterations

This study shows that yeast cells adapt to changes in mitochondrial DNA copy number through retrograde signaling and protein dosage compensation, allowing robust growth despite mtDNA fluctuations.

Division Asymmetry Drives Cell Size Variability in Budding Yeast

The paper identifies division asymmetry as the main driver of cell size variability in budding yeast, showing it outweighs G1/S size control effects.