Author

Kristen J. Wade

University of California, San FranciscoORCID 0000-0002-0338-5028Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:whole-genome sequencing· 3 Approach:statistical model· 2 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Danillo G. AugustoiD· 2 shared Jill A. HollenbachiD· 2 shared Adam RenscheniD· 1 shared Adam SantanielloiD· 1 shared Andrew Hill· 1 shared David D. PollockiD· 1 shared Elise N. GroveriD· 1 shared Elizabeth J. CarltoniD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBioinformatics

Danillo G. AugustoORCID

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3 papers

Recent·Most cited

Population genomics reveals multi-scale mechanisms sustaining schistosomiasis re-emergence in a near-elimination setting

Hannah D. Guss, Yannick Z. Francioli, Elise N. Grover, Andrew Hill, Wei Zou, Kristen J. Wade, Hamish Pike, Siddharth S. Gopalan, Liu Yang, Zhong Bo, David D. Pollock, Elizabeth J. Carlton, Todd A. Castoe

The paper uses population genomics to analyze Schistosoma japonicum re-emergence in Sichuan, China, revealing a diverse parasite population maintained in reservoirs and a regional transmission network.

PLoS neglected tropical diseases · Sep 8, 2026Peer-reviewedGenomics

MHConstructor: A high-throughput, haplotype-informed solution to the MHC assembly challenge

Kristen J. Wade, Rayo Suseno, Kerry Kizer, Jacqueline P. Williams, Juliano André Boquett, Stacy J. Caillier, Nicholas R. Pollock, Adam Renschen, Adam Santaniello, Jorge R. Oksenberg, Paul J. Norman, Danillo G. Augusto, Jill A. Hollenbach

MHConstructor provides a haplotype-informed, high-throughput pipeline for de novo MHC assembly from short read data, improving upon reference-based methods.

Genome biology · Oct 17, 2024Peer-reviewedBioinformatics

High-throughput complement component 4 genomic sequence analysis with C4Investigator

Wesley M. Marin, Danillo G. Augusto, Kristen J. Wade, Jill A. Hollenbach

The paper develops C4Investigator, a bioinformatic pipeline for high-throughput analysis of C4 gene variants from genomic data, revealing high poly-allelic variation in the 1000 Genomes Project Dataset.

HLA · Oct 29, 2023Peer-reviewedBioinformatics