Cancer BiologybioRxivPreprint
The ancestral haplotype of P2RX5 yields a B-cell surface marker and a multi-lineage immunotherapy target
Zhiwei Ang, Annette Castro, Luca Paruzzo…·Andrei Thomas‐Tikhonenko
The paper identifies P2RX5 as a new B-cell surface marker and multi-lineage immunotherapy target, showing its expression in B-cell malignancies and T-cell leukemia, and demonstrating the efficacy of P2RX5-directed therapies.
DOI 10.64898/2026.01.14.698748