Wenhan Chang

This study shows that type 2 diabetes reprograms bone marrow hematopoiesis and dysregulates immune signaling after stroke, leading to impaired immune responses and worsened outcomes.

This study evaluates hexokinase-2 inhibitors' effects on post-stroke inflammation and neuroprotection, finding that selective inhibitors reduce microglial activation and improve functional outcomes.

This study shows that neuronal CaSR regulates energy and skeletal metabolism by modulating hypothalamic function in mice, affecting growth, bone mass, and metabolic parameters.

The paper examines molecular and pathological changes in the suprachiasmatic nucleus across Alzheimer's disease stages, finding SCN-specific tau pathology and immune dysregulation.

This study examines the differential degeneration of wake- and sleep-modulating neurons in Alzheimer's disease, finding significant loss of orexinergic neurons and relative preservation of MCHergic neurons.

The paper investigates how extracellular calcium affects neuronal excitability and finds that the Calcium-sensing receptor (CaSR) modulates voltage-gated sodium channel (VGSC) activity, influencing action potential firing rates.