Ji Yi

This paper identifies an AKT1-TERT-FOXO3-MYC transcriptional complex that drives ERphagy and proteostasis in post-mitotic RPE cells under stress.

This paper develops threshold-free deep learning models for detecting swim bouts in larval zebrafish, showing improved precision over traditional methods and revealing behavioral patterns across genetic backgrounds.

This study identifies a diet-induced metabolic-immune axis linking gut microbiome changes to systemic immune aging and retinal degeneration in mice and AMD patients.

This paper introduces PI-SLO, a 3D imaging technique for volumetric single-cell imaging in living mouse retinas, enabling studies of microglial dynamics, vascular perfusion, and calcium fluxes.

This paper introduces a self-supervised algorithm to correct spatially variant aberrations in volumetric microscopy without PSF calibration or training data, enhancing image quality across large fields of view.

This paper introduces a self-adaptive oblique plane microscopy technique that enables high-speed volumetric imaging across microscopic to macroscopic scales in multi-cellular systems.

This study develops a multimodal imaging system combining VIS-OCT and PLIM-SLO to simultaneously capture retinal structure and capillary oxygen levels in mice.

This paper introduces a compact refractive AOSLO system for wide-field retinal imaging in mice, revealing microglial interactions with transplanted neurons and immune responses.