Author

Vishnu Suresh Babu

Johns Hopkins UniversityORCID 0000-0001-8104-8652Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Organism:mouse· 4 Assay:proteomics· 4 Research Focus:chromatin & epigenetic regulation· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Organism:C. elegans· 2

Frequent Co-Authors

Debasish SinhaiD· 4 shared Stacey Hose· 4 shared James T. HandaiD· 3 shared Sridhar BammidiiD· 3 shared Arkasubhra GhoshiD· 2 shared Dominique MeyeriD· 2 shared Ji YiiD· 2 shared Jiang X. QianiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersCell Biology

Debasish SinhaORCID

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4 papers

Recent·Most cited

Cell BiologyAutophagyPeer-reviewedOct 26, 2026

AKT1-phosphorylated TERT assembles a FOXO3-MYC transcriptional complex that drives ERphagy and proteostasis in post-mitotic RPE

Vishnu Suresh Babu, Sayan Ghosh, Sridhar Bammidi…·Debasish Sinha

This paper identifies an AKT1-TERT-FOXO3-MYC transcriptional complex that drives ERphagy and proteostasis in post-mitotic RPE cells under stress.

1 citation

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Cell BiologybioRxivPreprintApr 20, 2026

Gut-derived metabolic reprogramming drives immune aging and tissue degeneration

Sayan Ghosh, Victoria Koontz, Ying Xin…·Debasish Sinha

This study identifies a diet-induced metabolic-immune axis linking gut microbiome changes to systemic immune aging and retinal degeneration in mice and AMD patients.

DOI 10.64898/2026.04.14.718497

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Cell BiologyAging CellPeer-reviewedJul 15, 2025

βA3/A1-crystallin is an epigenetic regulator of histone deacetylase 3 (HDAC3) in the retinal pigmented epithelial (RPE) cells

Sujan Chatterjee, Sayan Ghosh, Zachary Sin…·Prasun Guha

The paper identifies βA3/A1-crystallin as an epigenetic regulator of HDAC3 in RPE cells, showing it enhances HDAC3 activity through CK2 interaction and InsP6 regulation, linking it to AMD pathogenesis.

6 citations

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ImmunologybioRxivPreprintJan 22, 2025

Attenuated adenosine mediated immune-dampening increases natural killer cell activity in early age-related macular degeneration

Archana Padmanabhan Nair, Sayan Ghosh, Vishnu Suresh Babu…·Arkasubhra Ghosh

The paper investigates immune alterations in early AMD, finding elevated NK cell activity and reduced adenosine, suggesting immune imbalance drives disease progression.

DOI 10.1101/2025.01.22.634301

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