GenomicsAging CellPeer-reviewed
Nanopore sequencing identifies a higher frequency and expanded spectrum of mitochondrial DNA deletion mutations in human aging
Amy R. Vandiver, Austin N. Hoang, Allen J. Herbst…·Jonathan Wanagat
This study uses nanopore sequencing to show that mtDNA deletion mutations increase exponentially with age and map to a wider genomic region, with novel algorithms improving detection accuracy.
32 citations