Taosheng Huang

This paper introduces an optogenetic system to modulate mitochondrial membrane potential by forming inter-mitochondrial contacts, showing it mitigates blue light damage in retinal cells and C. elegans.

The paper develops universal epigenetic clocks that accurately estimate age across mammalian tissues using DNA methylation data from 185 species.

The paper examines heteroplasmy variability in individuals with biparental mitochondrial DNA inheritance, finding significant inter-tissue and single-cell differences in paternal mtDNA transmission.

The paper analyzes mtDNA from individuals with biparental transmission and finds no evidence of intermolecular recombination, supporting strict maternal inheritance.