Ajoy Aloysius

This study compares fibroblast metabolism across species, finding spiny mice and rabbits exhibit a glycolytic preference and oxidative stress resilience across lifespan.

The paper develops universal epigenetic clocks that accurately estimate age across mammalian tissues using DNA methylation data from 185 species.

The paper shows RNA polymerase II pausing maintains quiescence by repressing transcription and primes cells for cell cycle re-entry.