Christian Bökel

The paper shows that E2f1/Dp activity regulates mitochondrial activity in Drosophila CySCs, linking cell cycle exit and differentiation.

The paper shows that innate immune signaling via Relish drives the elimination of losing stem cells during competition in Drosophila testis.

The paper analyzes transcriptomes of somatic cell populations in Drosophila testis to link metabolism and stemness, identifying gene expression patterns and signaling pathway differences.

The paper shows the Drosophila testis niche controls stem cell proliferation by repressing Hippo pathway genes without involving a binary fate decision between stemness and differentiation.

The paper develops a high throughput cell-based assay to quantify Hedgehog pathway activation by measuring Smoothened phosphorylation and identifies compounds that modulate this process.