Sean de la O

The paper analyzes the conservation and evolution of striatal interneurons across mammals, finding that TAC3 interneurons are conserved and that neuronal types evolve through redistribution and refinement.

This study uses single-nucleus ATAC-sequencing to analyze chromatin accessibility and RNA expression in developing mouse pancreas, identifying gene regulatory programs and transcription factors involved in cell fate determination.

This study shows Rab11 is essential for pancreas development, lumen formation, and endocrine mass by regulating epithelial morphogenesis and vesicle trafficking.

This study maps human fetal pancreatic development using scRNA-Seq and snATAC-Seq, identifying novel cell types and regulatory mechanisms, and highlights gene FEV's role in endocrine differentiation.