Author

Tyler Bierschenk

The University of Texas Southwestern Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

Ondine B. CleaveriD· 3 shared Neha H. AhujaiD· 2 shared Austin Mills· 1 shared Caitlin MaynardiD· 1 shared Christopher P. ChaneyiD· 1 shared D. Berfin AzizogluiD· 1 shared Denise K. MarcianoiD· 1 shared Denise Marciano· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersDevelopmental Biology

Ondine B. CleaverORCID

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3 papers

Recent·Most cited

Transient architecture of the embryonic pancreas determines endocrine mass

Ondine B. Cleaver, Neha Ahuja, Christopher P. Chaney, Tyler Bierschenk, Tuli Pramanik, Austin Mills, Peter Luo, Mitzy Cowdin, Jinlong Lin, Jun Tsunezumi, Kevin M. Dean, Denise Marciano, Thomas J. Carroll

This study shows that transient 3D epithelial architecture in the embryonic pancreas instructs lineage allocation and endocrine cell mass formation through Merlin-dependent membrane trafficking.

bioRxiv · Jul 1, 2026 · PreprintDevelopmental Biology

Characterization of Hippo Signaling Components in the Early Dorsal Pancreatic Bud

Neha H. Ahuja, Caitlin Maynard, Tyler Bierschenk, Ondine B. Cleaver

This paper investigates the expression and localization of Hippo signaling components during early pancreatic development in mice, finding distinct patterns of YAP1 and TAZ expression in progenitor and endocrine cells.

Gene Expression Patterns · Mar 11, 2025Peer-reviewedDevelopmental Biology

Rab11 is essential to pancreas morphogenesis, lumen formation and endocrine mass.

Haley Rose Barlow, Neha H. Ahuja, Tyler Bierschenk, Yadanar Htike, Luke Fassetta, D. Berfin Azizoglu, Juan Flores, Nan Gao, Sean de la O, Julie B. Sneddon, Denise K. Marciano, Ondine B. Cleaver

This study shows Rab11 is essential for pancreas development, lumen formation, and endocrine mass by regulating epithelial morphogenesis and vesicle trafficking.

Developmental Biology · May 10, 2023Peer-reviewedDevelopmental Biology