Dimitri Meistermann

The paper jointly profiles neuronal morphology and gene expression during iPSC differentiation to better understand neuronal development and disease modeling.

This study examines how maternal low protein diet affects reward circuit development in rats from childhood to adulthood, showing changes in palatable food preference and neural function.

DeconV is a probabilistic cell-type deconvolution method for bulk RNA-Seq data using scRNA-Seq references, offering comparable accuracy to Scaden with added interpretability through confidence intervals.

This study identifies a Nanog-dependent gene cluster that initiates epiblast specification in early mouse embryos, revealing a primary heterogeneity independent of NANOG, GATA6, and FGF signaling.

The paper develops an automated tool for annotating embryo morphokinetic parameters, showing high concordance with manual annotation in human and mouse embryos.