Claire Chazaud

This study shows Netrin-1 supports naive pluripotency in hESCs by modulating epigenetic and signaling pathways, with effects dependent on culture conditions.

The paper identifies a ligand/receptor trafficking clock in pluripotent stem cells that regulates self-renewal and abscission dynamics through cyclic turnover of Netrin-1 and its receptors.

The paper develops a species-agnostic multiplexing method for single-cell RNA sequencing in chick embryos, enabling accurate detection of treatment effects without batch correction.

The paper identifies Asgard, a STAT3-regulated lncRNA, which controls microRNA biogenesis and sequestration to maintain naive pluripotency in mouse embryonic stem cells.

This study identifies a Nanog-dependent gene cluster that initiates epiblast specification in early mouse embryos, revealing a primary heterogeneity independent of NANOG, GATA6, and FGF signaling.