A Nanog-dependent gene cluster initiates the specification of the pluripotent epiblast
Nicolas Allègre, Sabine Chauveau, Cynthia Dennis, Yoan Renaud, Dimitri Meistermann, Lorena Valverde Estrella, Pierre Pouchin, Michel Cohen‐Tannoudji, Laurent David, Claire Chazaud
This study identifies a Nanog-dependent gene cluster that initiates epiblast specification in early mouse embryos, revealing a primary heterogeneity independent of NANOG, GATA6, and FGF signaling.
Nature Communications · Jun 21, 2022Peer-reviewedDevelopmental Biology