Reza Dastvan

This study identifies dimer opening in CK-BB as a mechanism for sensing membrane curvature and regulating ATP regeneration under acidic conditions and substrate binding.

This study shows phosphorylation of IGF2BP1 and IGF2BP3 at a conserved serine acts as a configurational switch, altering their RNA binding domain arrangements and affecting mRNA regulation.

The paper investigates the mechanism of proton-coupled transport in the mycobacterial Spns transporter using spectroscopy, modeling, and mutagenesis, revealing how protonation and substrate binding influence conformational states and transport directionality.

This study identifies structural dynamics and regulatory mechanisms of SK1, revealing a novel inhibitory paradigm and insights for therapeutic development.

This study uses single-molecule techniques to show that RPA partially wraps ssDNA and that phosphorylation at Ser-384 modulates this wrapping.