Author

Simon Frerich

Institut für Schlaganfall- und DemenzforschungORCID 0000-0002-8275-6113Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Martin DichgansiD· 2 shared Amy FergusoniD· 1 shared Benno G. GesierichiD· 1 shared Cathie L. M. SudlowiD· 1 shared Christina KoupourtidouiD· 1 shared Christof HaffneriD· 1 shared Fabian Joachim TheisiD· 1 shared Frank KirchhoffiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Martin DichgansORCID

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2 papers

Recent·Most cited

NeuroscienceNature CommunicationsPeer-reviewedApr 3, 2024

Shared inflammatory glial cell signature after brain injury, revealed by spatial, temporal and cell-type-specific profiling of the murine cerebral cortex

Christina Koupourtidou, Veronika Schwarz, Hananeh Aliee…·Jovica Ninkovic

The paper identifies a shared inflammatory glial cell signature after brain injury using spatial and single-cell transcriptomics in mice, showing common injury-regulated genes across astrocytes, microglia, and oligodendrocyte precursor cells.

48 citationstop 1%

mousespatial transcriptomics

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Genetic & Genomic MedicineBrainPeer-reviewedJul 6, 2021

Whole-exome sequencing in 16,511 individuals reveals a role of the HTRA1 protease and its substrate EGFL8 in brain white matter hyperintensities

Rainer Malik, Nathalie Beaufort, Simon Frerich…·Martin Dichgans

The paper identifies rare variants in HTRA1 and its substrate EGFL8 associated with increased white matter hyperintensities using whole-exome sequencing data from 16,511 UK Biobank individuals.

44 citations

humanwhole-exome sequencing

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