Wei Lü

This study investigates how Shisa7 modulates GABAAR single-channel gating kinetics through single-channel recordings and kinetic analysis, revealing its role in reducing open probability and burst duration.

This study identifies Shisa7 phosphorylation at S405 as critical for GABAAR trafficking and function, leading to altered synaptic inhibition and neurodevelopmental behaviors in mice.

This study identifies how propofol excites lateral habenula neurons by enhancing presynaptic glutamate release, promoting sedation through increased synaptic excitation.

This study identifies distinct roles of GluN2A- and GluN2B-containing NMDA receptors in regulating tonic GABAergic inhibition in hippocampal neurons under physiological and pathological conditions.