Joan H.M. Knoll

This paper describes ADCI Online, a secure cloud-based platform for radiation dose estimation using dicentric chromosome assays, achieving results comparable to local systems in under 2 days.

ADCI-HT automates dicentric chromosome detection and dose estimation for large-scale radiation incidents, achieving high throughput and accuracy.

This paper improves automated cytogenetic biodosimetry by correcting false positive dicentric chromosomes to estimate partial body radiation exposure.

The paper improves radiation dose estimation by automating dicentric chromosome curation and metaphase cell selection, reducing false positives and increasing accuracy.

The paper presents a centromere detection algorithm for human metaphase chromosomes, achieving 87% accuracy by evaluating candidate locations using profile thickness measurements and correcting for sister chromatid separation.