Francisco J. Enguita

This study verifies nucleotide sequence reagents and cell line identities in circRNA papers and finds frequent errors in high-impact journals.

This study investigates how the DENV capsid protein interacts with single-stranded DNA, revealing structural changes that suggest molecular condensation and potential phase separation in complex formation.

The paper identifies miR-122-5p and miR-1247 as regulators of Th17 and Th1 cell functions in autoimmune inflammation, affecting EAE severity.

This study investigates how the PINK1-G411S mutant affects PINK1 function, showing increased kinase stability and mitochondrial-linked functions through molecular dynamics analysis.

This study identifies APP's role in regulating NMDAR function during development and aging, showing distinct mechanisms in postnatal and aged stages.

This study identifies DISC1 as a key molecule for cardiomyocyte resilience after myocardial infarction, showing its role in cardioprotection through interaction with GSK3β and its relevance in cardiac health following coronary artery bypass grafting.

The paper identifies a lncRNA signature associated with SARS-CoV-2 infection through transcriptomic analysis and functional correlation studies.

The paper identifies miR-2392 as a miRNA involved in SARS-CoV-2 infection, showing its role in inflammation, glycolysis, and hypoxia, and develops a miRNA-based therapeutic targeting it.

This study shows that Hsp27 reduces glycation-induced toxicity and aggregation of α-synuclein in cellular models.

The paper maps the genome-wide association of capsid proteins with viral RNA in Dengue and Zika viruses, showing non-uniform binding patterns and sequence preferences.

The paper introduces miRNAtools, a web repository of miRNA analysis tools and tutorials for advanced training in miRNA functional analysis.