Author

Andrew N. Hogan

National Institutes of HealthORCID 0000-0003-1610-0447Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Ake Tzu-Hui LuiD· 2 shared Amin HaghaniiD· 2 shared Joseph Alan ZolleriD· 2 shared Robert T. BrookeiD· 2 shared A ArnesoniD· 1 shared A. J. Levine· 1 shared A. R. Lim· 1 shared Abhijeet KapooriD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersDevelopmental Biology

Ake Tzu-Hui LuORCID

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3 papers

Recent·Most cited

Pharmacology & ToxicologyProceedings of the National Academy of SciencesPeer-reviewedOct 10, 2024

Development of quantitative high-throughput screening assays to identify, validate, and optimize small-molecule stabilizers of misfolded β-glucocerebrosidase with therapeutic potential for Gaucher disease and Parkinson's disease

Darian Williams, Logan M. Glasstetter, Tiffany T. Jong…·Yu Chen

This paper develops high-throughput assays to identify and optimize small-molecule stabilizers of misfolded β-glucocerebrosidase, showing NCGC326 reverses pathological accumulation and synergizes with proteostasis regulators.

32 citationstop 1%

humanproteomics

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Developmental BiologyNature AgingPeer-reviewedAug 10, 2023

Universal DNA methylation age across mammalian tissues

Ake Tzu-Hui Lu, Zhe Fei, Amin Haghani…·June Mergl

The paper develops universal epigenetic clocks that accurately estimate age across mammalian tissues using DNA methylation data from 185 species.

396 citationstop 1%

mousehuman

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Developmental BiologybioRxivPreprintMar 30, 2021

Epigenetic clock and methylation studies in dogs

Steve Horvath, Ake Tzu-Hui Lu, Amin Haghani…·Elaine A. Ostrander

This paper develops epigenetic clocks for dogs to estimate age and mortality risk, and identifies methylation sites linked to breed weight and lifespan.

6 citations

DNA methylationstatistical model

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