Author

Hope S. Rugo

City Of Hope National Medical CenterORCID 0000-0001-6710-4814Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Andrei GogaiD· 2 shared Andrew R. Beardsley· 1 shared Atul Janardhan ButteiD· 1 shared Céline I. MahieuiD· 1 shared Charles A. Berdan· 1 shared Christopher O’Brien· 1 shared Daniel C. LiebleriD· 1 shared Daniel K. NomuraiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Andrei GogaORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintApr 29, 2026

MYC Overexpression Confers Sensitivity to TACC3 Inhibition for Triple-Negative Breast Cancer

Mauricio Jacobo Jacobo, July Aung, Christopher O’Brien…·Andrei Goga

This study identifies TACC3 as a vulnerability in MYC-overexpressing triple-negative breast cancers, showing that its inhibition induces cytotoxicity and inflammatory responses.

DOI 10.64898/2026.04.28.721171

humanbulk RNA-seq

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Cancer BiologyNature CommunicationsPeer-reviewedAug 20, 2025

Tumor cell-adipocyte gap junctions activate lipolysis and contribute to breast tumorigenesis

Jeremy Williams, Roman Camarda, Serghei Malkov…·Andrei Goga

The paper shows that gap junctions between breast cancer cells and adipocytes transfer cAMP, activating lipolysis in the tumor microenvironment to support tumor growth.

17 citationstop 5%

humanmouse

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