Author
University of HelsinkiORCID 0000-0003-4844-1289Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Mauricio Jacobo Jacobo, July Aung, Christopher O’Brien…·Andrei Goga
This study identifies TACC3 as a vulnerability in MYC-overexpressing triple-negative breast cancers, showing that its inhibition induces cytotoxicity and inflammatory responses.
Ruixian Liu, July Aung, Aino Peura…·Juha T. Klefström
The paper identifies microtubule inhibitors as inducers of immunogenic cell death in MYChigh TNBC, linking MYC-dependent DAMP release to immune activation and tumor protection.
Johanna M. Anttila, Mariel Savelius, Juhi Somani…·Juha T. Klefström
This study identifies enhanced mitochondrial respiration and glutamine-dependent TCA cycle as vulnerabilities in MYChigh breast cancer cells, showing synthetic lethality with complex I inhibitors.